Health News: [cancer]

Health Notes: Tyrod Taylor issues cancer challenge to Hampton Roads residents Daily Press Tue, 24 Jan 2012 14:02 PM PST Baltimore Ravens quarterback Tyrod Taylor, is challenging individuals in Hampton Roads, where he grew up, to raise at least $212 each in 2012 to help the American Cancer Society save more lives through Relay For Life . South Shore Hospital gets $5m gift Boston Globe Tue, 24 Jan 2012 14:00 PM PST South Shore Hospital has received a $5 million gift that it plans to use to boost cancer care, orthopedics, home care, and to help build a 60-bed expansion. The gift from the McKim Family Foundation is the largest in the hospital’s 90-year history. Braintree native Alan McKim founded the environmental cleanup company Clean Harbors in 1980. McKim said the hospital touches hundreds of lives in the ... Women with Certain Type of Ovarian Cancer and BRCA Gene Mutation Have Improved Survival at 5 Years Newswise Tue, 24 Jan 2012 14:00 PM PST Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved 5-year overall survival, with BRCA2 carriers having the best prognosis, according to a study in the January 25 issue of JAMA. Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer [Original ... Journal of the American Medical Association Tue, 24 Jan 2012 13:58 PM PST Context Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in BRCA1 or BRCA2 . A recent article suggested that BRCA2 -related EOC was associated with an improved prognosis, but the effect of BRCA1 remains unclear. Objective To characterize the survival of BRCA carriers with EOC compared with noncarriers and to determine whether BRCA1 and ... Donald G. “Pops” Bango, Aug. 19, 1941-Jan. 23, 2012 The Sandusky Register Tue, 24 Jan 2012 13:57 PM PST Donald G. “Pops” Bango, 70, of Sandusky, went home to a better place, Monday, Jan. 23, 2012, in Firelands Regional Medical Center, after a brief battle with cancer. read more Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients [Grand Rounds] Journal of the American Medical Association Tue, 24 Jan 2012 13:57 PM PST Unlike professional caregivers such as physicians and nurses, informal caregivers, typically family members or friends, provide care to individuals with a variety of conditions including advanced age, dementia, and cancer. This experience is commonly perceived as a chronic stressor, and caregivers often experience negative psychological, behavioral, and physiological effects on their daily lives ... Marcia Gardner, Education Director at DC-Area Signature Theatre, Dies Playbill Tue, 24 Jan 2012 13:57 PM PST Marcia Gardner, a longstanding figure at the Signature Theatre in Arlington, VA, died Jan. 20 at her home in Alexandria after a battle with cancer. Unwrapping the Implications of BRCA1 and BRCA2 Mutations in Ovarian Cancer [Editorial] Journal of the American Medical Association Tue, 24 Jan 2012 13:57 PM PST Three large studies have demonstrated improved survival in BRCA -associated ovarian cancers compared with sporadic ovarian cancers. 1 , 2 , 3 These trials have combined BRCA1 and BRCA2 mutation carriers because of the relative rarity of BRCA1 and BRCA2 mutations, which only account for approximately 10% and 5% of unselected cases of serous ovarian cancer, respectively. BRCA1 and BRCA2 Mutations in Ovarian Cancer [Letters] Journal of the American Medical Association Tue, 24 Jan 2012 13:57 PM PST To the Editor: Dr Yang and colleagues found significantly better progression-free survival rates in women with ovarian cancer and BRCA2 mutations compared with BRCA1 mutations or wild-type BRCA . 1 In addition, they reported that BRCA2 mutations were associated with a 100% primary chemotherapy sensitivity rate compared with 82% for BRCA wild-type and 80% for BRCA1- mutated cases, suggesting an ... BRCA1 and BRCA2 Mutations in Ovarian Cancer--Reply [Letters] Journal of the American Medical Association Tue, 24 Jan 2012 13:56 PM PST In Reply: Drs Buerkle and Tempfer asked whether differences in progression-free survival and primary chemotherapy response between BRCA1 - and BRCA2 -mutated cases could be the result of unbalanced distribution of disease stages and extent of cytoreduction.

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